ULTRAPURE WATER
WHAT IS ULTRAPURE WATER?
Ultrapure water is a type of water that has been purified according to the highest standards. Contaminants are removed specifically: organic and inorganic matter, suspended particles and dissolved particles. In conclusion, containing only H20, and H+ and OH- ions in equilibrium.
Therefore, ultrapure water conductivity is about 0.055 uS/cm at 25ºC (77 ºF), also expressed as resistivity of 18.2 MOhm. Ultra-pure water is mainly used in the semiconductor and pharmaceutical industry.
In other words, it’s known as Water For Injection (WFI), High Purity Water and De ionized Water (DI). In fact, usually all of this terms refers to the same properties in water.
HOW to make ultrapure water?
Processes like membrane filtration or ion exchange produce ultrapure water. The ultimate conductivity is 10 uS/cm so these process are used to reach that. Next, the demineralized water is processed through a high performance Mixed Bed or by Electro deionization.

OUR SOLUTION
Complete flowchart for ultrapure water production showing the ADVANCEES systems. This flowchart varies based on raw water quality and customer’s requirement. Many combinations are possible. More importantly, the best solution needs to accommodate the minimum life cycle cost, such as low operating cost, low maintenance, and easy to operate and monitor.
THE BEST ULTRAPURE WATER PROCESS
What Is Ultrapure Water?
Applications That Require Ultrapure Water
Semiconductor Manufacturing
Ultrapure water is critical in the production of semiconductor chips and electronic components. It ensures that delicate microcircuit surfaces remain free of ionic or particulate contamination during rinsing and etching processes.
Pharmaceutical Industry
In drug manufacturing, research, and development, ultrapure water must meet stringent quality standards to maintain product safety and efficacy.
Biotechnology
Processes like DNA sequencing, cell culturing, and protein purification depend on ultrapure water, as even minimal contaminants can compromise results.
Ultrapure Water Treatment Methods
Several advanced technologies are used to produce ultrapure water. Each method plays a role in removing specific types of contaminants:
Distillation
This process heats water to create steam, then condenses it to remove impurities such as heavy metals and particulates.
Deionization (DI)
Ion exchange resins are used to remove positively and negatively charged ions, significantly reducing water conductivity.
Reverse Osmosis (RO)
Using pressure, water is pushed through semi-permeable membranes that filter out dissolved salts and organic compounds.
Electrodeionization (EDI)
A continuous process that uses electric currents and ion-exchange membranes to eliminate residual ions—without the need for chemical regenerants.
Ultrafiltration
Ultrafiltration membranes with microscopic pores physically remove bacteria, viruses, and particulates.
UV and Ozone Disinfection
These methods break down and destroy microbial and organic contaminants, enhancing water purity without chemical additives.
Monitoring Ultrapure Water Quality
To ensure consistent purity, ultrapure water systems rely on high-precision monitoring equipment:
- Conductivity Meters: Measure the concentration of dissolved ions in the water.
- TOC Analyzers (Total Organic Carbon): Detect trace levels of organic contamination that could impact sensitive applications.
Sustainability in Ultrapure Water Production
While ultrapure water is essential, its production can be energy-intensive. The water treatment industry is advancing toward more sustainable systems that reduce water waste, lower energy consumption, and incorporate environmentally responsible practices—helping meet both regulatory and ethical goals.